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Targeted therapy: questions to ask your doctor

Carcinoma - targeted; Squamous cell - targeted; Adenocarcinoma - targeted; Lymphoma - targeted; Tumor - targeted; Leukemia - targeted; Cancer - targeted

Definition

You are having a targeted therapy to try to kill cancer cells. You may receive targeted therapy alone or also have other treatments at the same time. Your health care provider may need to follow you closely while you are having targeted therapy. You will also need to learn how best to care for yourself during this time.

Below are some questions you may want to ask your doctor.

Questions

Is targeted therapy the same as chemotherapy?

Do I need someone to bring me in and pick me up after the treatment?

What are the known side effects? How soon after starting my treatment will I experience the side effects?

Am I at risk for infections?

What foods should I not eat so that I do not get an infection?
Is my water at home OK to drink? Are there places I should not drink the water?
Can I go swimming?
What should I do when I go to a restaurant?
Can I be around pets?
What immunizations do I need? Which immunizations should I stay away from?
Is it OK to be in a crowd of people? Do I have to wear a mask?
Can I have visitors over? Do they need to wear a mask?
When should I wash my hands?
When should I take my temperature at home?

Am I at risk for bleeding?

Is it OK to shave?
What should I do if I cut myself or start bleeding?

Are there any medicines I should not take?

Are there any other medicines I should keep on hand?
What over-the-counter medicines am I allowed to take?
Are there any vitamins and supplements I should and should not take?

Do I need to use birth control?

Will I be sick to my stomach or have loose stools or diarrhea?

How long after I start targeted treatment might these problems start?
What can I do if I am sick to my stomach or have diarrhea?
What should I be eating to keep my weight and strength up?
Are there any foods I should avoid?
Am I allowed to drink alcohol?

Will my hair fall out? Is there anything I can do about it?

Will I have problems thinking or remembering things? Can I do anything that might help?

What should I do if I get a rash?

Do I need to use a special kind of soap?
Are there creams or lotions that can help?

If my skin or eyes are itchy, what can I use to treat this?

What should I do if my nails start to break?

How should I take care of my mouth and lips?

How can I prevent mouth sores?
How often should I brush my teeth? What type of toothpaste should I use?
What can I do about dry mouth?
What should I do if I have a mouth sore?

Is it OK to be out in the sun?

Do I need to use sunscreen?
Do I need to stay indoors during cold weather?

What can I do about my fatigue?

When should I call the doctor?

References

Do KT, Kummar S. Therapeutic targeting of cancer cells: era of molecularly targeted agents. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 26.

National Cancer Institute website. Targeted cancer therapies. www.cancer.gov/about-cancer/treatment/types/targeted-therapies/targeted-therapies-fact-sheet. Updated May 31, 2022. Accessed October 21, 2022.

Sohal DPS, Khorana AA. Principles of cancer therapy. In: Wing EJ, Schiffman FJ, eds. Cecil Essentials of Medicine. 10th ed. Philadelphia, PA: Elsevier; 2022:chap 56.

Stegmaier K, Sellers WR. Targeted therapies in oncology. In: Orkin SH, Fisher DE, Ginsburg D, Look AT, Lux SE, Nathan DG, eds. Nathan and Oski's Hematology and Oncology of Infancy and Childhood. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 44.

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Review Date: 8/15/2022

Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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