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Allergen

Positive reaction ...Positive reaction to allergen

Definition

An allergen is a substance that can cause an allergic reaction. In some people, the immune system recognizes allergens as foreign or dangerous. As a result, the immune system reacts by making a type of antibody called immunoglobulin E (IgE) to defend against the allergen. This reaction leads to allergy symptoms.

Information

Common allergens include:

Animal proteins and animal dander
Dust
Drugs (such as antibiotics or medicines you put on your skin)
Foods (such as egg, peanut, milk, nuts, soy, fish, animal meat, and wheat)
Fungal spores
Insect and mite feces
Insect bites and stings (their venom)
Natural latex rubber
Pollen

References

Stewart GA, Robinson C. The structure and function of allergens. In: Burks AW, Holgate ST, O'Hehir RE, et al, eds. Middleton's Allergy: Principles and Practice. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 26.

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Review Date: 2/2/2023

Reviewed By: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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