Pancreatitis - blood amylase DefinitionAmylase is an enzyme that helps digest carbohydrates. It is made primarily in the pancreas and the glands that make saliva, and can be found at low levels in other parts of the body. When the pancreas is diseased or inflamed, it releases increased amounts of amylase into the blood. A test can be done to measure the level of this enzyme in your blood. Amylase may also be measured with a urine amylase test. How the Test is PerformedA blood sample is taken from a vein. How to Prepare for the TestNo special preparation is needed. However, you should avoid alcohol before the test. The health care provider may ask you to stop taking drugs that may affect the test. Do not stop taking any medicines without first talking to your provider. Drugs that can increase amylase measurements include:
How the Test will FeelYou may feel slight pain or a sting when the needle is inserted to draw blood. Afterward, there may be some throbbing. Why the Test is PerformedThis test is most often used to diagnose or monitor acute pancreatitis. It may also detect some digestive tract problems. The test may also be done for the following conditions: Normal ResultsThe normal range is 40 to 140 units per liter (U/L) or 0.38 to 1.42 microkat/L (µkat/L). Normal value ranges may vary slightly among different laboratories. Some laboratories use different measurement methods. Talk to your provider about the meaning of your test results. What Abnormal Results MeanIncreased blood amylase level may occur due to:
Decreased amylase level may occur due to:
RisksSlight risks from having blood drawn may include:
ReferencesCrockett SD, Wani S, Gardner TB, Falck-Ytter Y, Barkun AN; American Gastroenterological Association Institute Clinical Guidelines Committee. American Gastroenterological Association Institute guideline on initial management of acute pancreatitis. Gastroenterology. 2018;154(4):1096-1101. PMID: 29409760 pubmed.ncbi.nlm.nih.gov/29409760/. Forsmark CE. Pancreatitis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 135. Siddiqi HA, Rabinowitz S, Axiotis CA. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 23. Vege SS. Acute pancreatitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 58. | |
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Review Date: 2/28/2023 Reviewed By: Jacob Berman, MD, MPH, Clinical Assistant Professor of Medicine, Division of General Internal Medicine, University of Washington School of Medicine, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. | |
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Blood test
