Biopsy - upper airway DefinitionUpper airway biopsy is surgery to remove a small piece of tissue from the nose, mouth, and throat area. The tissue will be examined under the microscope by a pathologist. How the Test is PerformedThe health care provider will spray a numbing medicine in your mouth and throat. A metal tube is inserted to hold your tongue out of the way. Another numbing medicine flows through the tube down the back of the throat. This may cause you to cough at first. When the area feels thick or swollen, it is numb. The test may also be performed under general anesthesia, so that you will be asleep and not feel pain. The provider looks at the abnormal area, and removes a small piece of tissue. It is sent to the laboratory for examination. How to Prepare for the TestDO NOT eat for 6 to 12 hours before the test. Tell your provider if you take a blood thinner, such as aspirin, clopidogrel, or warfarin, when you schedule the biopsy. You may need to stop taking them for a little while. Never stop taking any medicines without first talking to your provider. How the Test will FeelAs the area is being numbed, you may feel like there is fluid running down the back of your throat. You may feel the need to cough or gag. And you may feel pressure or mild tugging. When the numbness wears off, your throat may feel scratchy for several days. After the test, the cough reflex will return in 1 to 2 hours. Then you may eat and drink normally. Why the Test is PerformedThis test may be done if your provider thinks there is a problem with your upper airway. It may also be done with a bronchoscopy. Normal ResultsThe upper airway tissues are normal, with no abnormal growths. What Abnormal Results MeanDisorders or conditions that may be discovered include:
RisksRisks for this procedure include:
There is a risk of choking if you swallow water or food before the numbness wears off. ReferencesBarbareschi M, Mengoli MC, Cavazza A. Nonneoplastic pathology of the large and small airways. In: Smith ML, Leslie KO, Wick MR, eds. Practical Pulmonary Pathology. 4th ed. Philadelphia, PA: Elsevier; 2024:chap 9. Mason JC. Rheumatic diseases and the cardiovascular system. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 97. White V, Ruparelia P. Respiratory disease. In: Feather A, Randall D, Waterhouse M, eds. Kumar and Clark's Clinical Medicine. 10th ed. Philadelphia, PA: Elsevier; 2021:chap 28. Yu DH, Feller-Kopman D. Tracheobronchial endoscopy. In: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 71. | |
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Review Date: 11/29/2022 Reviewed By: Josef Shargorodsky, MD, MPH, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. | |
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Upper airway test
Bronchoscopy
Throat anatomy
