Cardiac tumor - myxoma; Heart tumor - myxoma DefinitionAn atrial myxoma is a noncancerous tumor in the upper left or right side of the heart. It most often grows on the wall that separates the two sides of the heart. This wall is called the atrial septum. CausesA myxoma is a primary heart (cardiac) tumor. This means that the tumor started within the heart. Most heart tumors start somewhere else. Primary cardiac tumors such as myxomas are rare. About 75% of myxomas occur in the left atrium of the heart. They most often begin in the wall that divides the two upper chambers of the heart. They can occur in other intra-cardiac sites as well. Atrial myxomas are sometimes linked with valve obstruction stenosis and atrial fibrillation.   Myxomas are more common in women. About 1 in 10 myxomas are passed down through families (inherited). These tumors are called familial myxomas. They tend to occur in more than one part of the heart at a time, and often cause symptoms at a younger age. SymptomsMany myxomas will not cause symptoms. These are often discovered when an imaging study (echocardiogram, MRI, CT) is done for another reason. Symptoms may occur at any time, but often they go along with a change in body position. Symptoms of a myxoma may include:
The symptoms and signs of left atrial myxomas often mimic mitral stenosis (narrowing of the valve between the left atrium and the left ventricle). Right atrial myxomas rarely produce symptoms until they have grown to be quite large (5 inches wide, or 13 cm). Other symptoms may include:
Exams and TestsThe health care provider will perform a physical exam and listen to your heart through a stethoscope. Abnormal heart sounds or a murmur may be heard. These sounds may change when you change body position. Imaging tests may include:
You may also need blood tests including:
TreatmentSurgery is needed to remove the tumor, especially if it is causing heart failure symptoms or an embolism. Outlook (Prognosis)Untreated, a myxoma can lead to an embolism (tumor cells or a clot that breaks off and travels in the bloodstream). This can lead to a blockage of blood flow. Pieces of the tumor can move to the brain, eye, or limbs. If the tumor grows inside the heart, it can block blood flow, causing symptoms of obstruction. Possible ComplicationsComplications may include:
ReferencesLenihan DJ, Reardon MJ, Hundley WG. Tumors affecting the cardiovascular system. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 98. Tazelaar HD, Maleszewski JJ. Tumors of the heart and pericardium. In: Fletcher CDM, ed. Diagnostic Histopathology of Tumors. 5th ed. Philadelphia, PA: Elsevier; 2021:chap 2. | |
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Review Date: 5/27/2024 Reviewed By: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. | |
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Left atrial myxoma
Right atrial myxom
